The term epilepsy implies episodic seizure disorders having different pathologies that have been classified according to the location and extent of the seizure process within the brain.
Fundamentally, seizures are of two types: Partial or generalized. This classification is based on the fact that the extent of cortical involvement and the neuroanatomic mechanism of expression, differs between the two groups.
Hippocampal sclerosis, also known as mesial temporal sclerosis or Ammon’s horn sclerosis, is characterized by neuronal loss and gliosis and is the most common pathology (50-70 %) found in refractory epilepsy. This pathology causes “complex partial seizures” in short CPS, which is also known as psychomotor epilepsy. Sclerotic hippocampal formation is identifiable in 60-80 % of CPS patients and according to the epileptogenic focus concept, it constitutes the origin of the ictal activity.
When we rewieved the literature, almost all of the centers working on epilepsy carry out the same diagnostic procedures such as;
-Detailed neurological examination,
-Electrophysiological tests and
-Magnetic Resonance Imaging.
MRI is an effective method to localize and characterize the lesions in the cases with CPS. Some specific imaging protocols can also be used for more detailed evaluation of the temporal lobes. For example, we prefer to use high resolution FSE Devamını Oku…